منابع مشابه
Prognostic and predictive markers for the new immunotherapies.
Blocking the programmed cell death 1 (PD-1) pathway with monoclonal antibodies has shown promising antitumor responses in clinical trials, with less toxicity than has been seen with prior immune therapies such as interleukin 2 and ipilimumab. Pembrolizumab, an anti-PD-1 antibody, recently gained US Food and Drug Administration (FDA) accelerated approval for the treatment of patients with ipilim...
متن کاملPrognostic markers for urologic cancers.
© The Canadian Journal of UrologyTM; 23(1); February 2016 Address correspondence to Dr. Jay D. Raman, Department of Urology, Penn State Milton S. Hershey Medical Center, 500 University Drive, BMR c4830F, Hershey, PA 17033 USA Prognostic markers for urologic cancers Jay D. Raman, MD Department of Urology, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA Referring to the ar...
متن کاملPrognostic and Predictive Clinical, Pathological and Molecular Markers for Oral Squamous Cell Carcinoma: review of articles
Approximately 90% of all head and neck malignancies and 94% of oral malignancies are squamous cell carcinoma (SCC). Tobacco smoking is considered as the most important causative agent for SCC. Despite aggressive and multidisciplinary treatment approaches, there has been no significant improvement in 5-year survival over the past 20 years. Several prognostic and predictive clinical, pathological...
متن کاملAssociations between diet, gut microbiota and markers of CRC risk
Background Recent advances in our understanding of the contributions of gut microbiota to host metabolism have renewed research interest in how distortions in microbiota activities correlate with health status. While extensive microbiota surveys have already revealed the complexity of microbiota dynamics there is a need to better understand mechanisms through which microbiota can affect host me...
متن کاملIX. Chronic lymphocytic leukaemia: new genetic markers as prognostic factors.
In Western countries, chronic lymphocytic leukaemia (CLL) is the most frequent mature B-cell malignancy [1]. The course of CLL ranges from very indolent, with a nearly normal life expectancy, to rapidly progressive leading to early death. Understand the genetic basis of CLL may help in clarifying the molecular determinants of this clinical heterogeneity and improve patients’ prognostication. Re...
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ژورنال
عنوان ژورنال: Nature Reviews Clinical Oncology
سال: 2010
ISSN: 1759-4774,1759-4782
DOI: 10.1038/nrclinonc.2010.29